An eight part series of hour-long episodes will be produced, hosted by the hugely popular Eamonn Holmes and produced by 5Production.
Each week two teams of celebrities and comedians go head-to-head over a series of fun and cheeky games and challenges – to be revealed nearer to transmission - with a host of surprises in store for viewers.
The show will see two teams of three panelists with regular team captains, as Eamonn Holmes offers the show his "uniquely witty take".
Eamonn said: "If you are in a relationship, single, or just nosey about who's dating who, this show is for you.
"Whether you are young or old you'll have something to contribute or learn from our celebrity panellists and games. And if you still can't get your head around it then It's not me - It's You!"
The team captains for It’s Not Me, It’s You will be confirmed in the coming weeks and the series will air over the summer on Channel 5.