The 'Domino' singer joined the show in its first series last year alongside Will.i.am, Danny O'Donoghue and Sir Tom Jones, but won't be returning for a third series.
In a statement, Jessie said: "I’ve absolutely loved my time on The Voice and I hope everyone saw and knows how passionately I felt about the show.
"However, I can’t wait to promote my new record around the world and that has to take priority. I shall be keeping a very close eye on series three, showing my support in every way I can and [I] really hope that in some way I can be part of the show.”
Mark Linsey, Controller of BBC Entertainment Commissioning, commented: “We’re so sorry to see Jessie go as she’s been an exceptional coach on – and an advocate for – The Voice, but we totally support her decision to leave due to touring commitments overseas."
He added: "We very much hope that Jessie will remain part of the show and come back and perform for us next series. In the meantime we will now start the search for a new coach.”
It remains to be seen what this means for the other coaches, who had said they would only be back if they were all back together.
“I’ve been asked to do series three, but it would depend on who else was there and it would be a hard decision. I feel like I’m married to Jessie so it would be weird if she wasn’t there. It’s like cheating," Will said.
And Sir Tom agreed: "The four of us make a great team — one without the other wouldn’t work."
The Voice 2014 will air on BBC One next Spring.