Courtney Act’s Christmas Extravaganza will air this evening, Christmas Eve (Monday, December 24) from 11:05PM.
According to C4, the format is the "world's first Dragazine show".
It will see the glamorous RuPaul's Drag Race favourite chat to celebrity guests and present studio items and music numbers.
She'll be joined by music acts including Leona Lewis, Little Mix and Zara Larsson.
Paralympic gold medallist Jonnie Peacock gets a full drag makeover, and in a UK exclusive Courtney is also joined by Drag Race icons Adore Delano, Bianca Del Rio and Darienne Lake.
Discussing the show, Courtney said: “It's bloody gay. It's so much fun. It's nothing like anything that's on television at the moment, that I've seen.
"I’ve been trying to be a good new person who is living in the UK by watching as many TV shows as I can, old and new. It's more like an old Morecambe and Wise special or a Judy Garland Christmas special."
She told DigitalSpy: "There's dancers and costumes and special guests and giant candy canes on wheels that the dancers whizz around, and giant Christmas presents that Leona Lewis and I sit on top of and sing a duet. Then there's a giant rainbow.
"We start off very traditional. We lull the UK family audience who are sitting at home on Christmas Eve just enjoying a camp bit of entertainment, but in the very traditional Christmas aesthetic. But then we sort of take them on a journey and end with rainbows and rainbow confetti."
Bosses have ordered just the one-off 60-minute special at the moment, with a series likely to follow if it proves successful.
Courtney said: "This is my show and I say come on in, all you heroic misfits, those of you who are a bit chipped around the edges… I want to welcome you all.
"You bring the open minds and I’ll bring the open bar and we’ll meet in the middle for a gay old time!"
A non-broadcast pilot was filmed in May, under the name 'Up Late and Courtney Act'.
Courtney started out auditioning for Australian Idol in 2003, before she rose to fame on the sixth season of RuPaul's Drag Race in 2014.
She reached the grand final, finishing as joint runner-up to Bianca Del Rio.
Following an appearance on MTV's celebrity dating show Single AF, Courtney joined Celebrity Big Brother in January.
After 32 days in the house, viewers crowned her the series champion, with 49.43% of the public vote.