Deborah took aim at Tom's reaction to Sam and Ellie's kiss, which last night caused rows and tears in the house.
Deborah said: "Yesterday there was thunder in the house. Tom has no reason to be involved in nobody's business in the house.
"I can see him as soon as they said 'we kissed', he's looking at Kieran. Be your own man! If you feel something go and speak to her. "
She added: "You're a big boy, you're pumping muscles, it's okay Tom, it's not your fight, it's Ellie.
"I just think Tom is here for the wrong reasons, he's always in somebody's business, just grow up.
"I don't know what size feet you wear, whatever it is go to size 10 because you're acting like a little boy. I'm fed up, I'm just so fed up."
Last night's highlights saw Sam Chaloner and Ellie Young enjoy a smooch on the kitchen floor, which they kept secret from the other housemates.
Until yesterday, that is, and the revelation of the kiss caused things to erupt and it all ended in tears.
With the housemates drinking, a game of Never Have I Ever saw Ellie reveal all of her and Sam's kiss to the group.
"Never have I ever kissed Sam before," she told her fellow housemates before sipping her drink.
The revelation caused drama which isn't too surprising given a number of housemates warning Ellie off Sam.
Deborah and Charlotte have both been seen telling Ellie to keep away from the newbie, suggesting he was just using her.
The gossip that the pair had kissed didn't go down well, with Chanelle particularly upset.
But Ellie insisted: "We're here to have a good time, I'm not being funny, we're here to have a laugh."
Big Brother 2017 airs tonight at 9PM on Channel 5.